fibrinopeptide a การใช้

• Reptilase also differs from thrombin by releasing fibrinopeptide A, but not fibrinopeptide B, in its cleavage of fibrinogen.
• First, thrombin cleaves fibrinopeptide A and B located on the N-terminus of the fibrinogen alpha and beta chains respectively.
• :Selective cleavage of Arg-bond in fibrinogen, to form fibrin, and release fibrinopeptide A . The specificity of further degradation of fibrinogen varies with species origin of the enzyme
• Other study found using a proteomic analysis of the CSF that the peak intensity of the signals corresponding to Secretogranin II and Protein 7B2 were significantly upregulated in RRMS patients compared to PrMS ( p < 0.05 ), whereas the signals of Fibrinogen and Fibrinopeptide A were significantly downregulated in CIS compared to PrMS patients